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Data Sources: Centers for Medicare & Medicaid Services (CMS), Medicare Provider Utilization and Payment Data
Disclaimer: This site is an independent journalism project. Data analysis and editorial content are not affiliated with or endorsed by CMS or any government agency. All spending figures are based on publicly available Medicare payment records.
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ยฉ 2026 OpenMedicare. Independent data journalism. Built by TheDataProject.ai

Methodologyโ€ขDownload Data
  1. Home
  2. Providers
  3. Biotheranostics, Inc.
๐Ÿ”ฌ
Organization

Biotheranostics, Inc.

NPI: 1043344435
San Diego, CA
10 years of data
Clinical Laboratory
$160.7M
Total Payments
43
Beneficiaries
52.0K
Services
1.51x
Markup Ratio

Peer Comparison

99th
percentile in specialty
This provider$160.7M
Specialty median$1.9M
Rank #58 of 232 in specialty

๐Ÿ“‹ Key Findings

1Billed $160.7M over 10 years
21.51x markup ratio
399th percentile in Clinical Laboratory by payments
4Payments surged 92% in 2021
52 procedures with >3x markup
โœ“ No flags detected

๐Ÿ”Ž Data Analysis

This provider's $160.7M in total Medicare payments ranks in the 99th percentile of Clinical Laboratory providers nationally.

Medicare payments to this provider grew 621% from 2014 to 2023.

62% of their billing comes from a single procedure code (81518 โ€” Mrna gene analysis of 11 genes in breast tumor tissue).

AI-generated analysis based on Medicare payment data.

Annual Medicare Payments

Annual Services Provided

Avg Payment per Service

Markup Ratio Over Time

๐Ÿ“ˆ

Notable: Payments increased 92% in 2021

Year-over-year payment surges can indicate changes in practice volume, new services, or billing pattern shifts.

Submitted Charges vs. Medicare Payments

Average per-service amounts submitted by the provider compared to what Medicare actually paid โ€” the gap represents the markup.

YearAvg SubmittedAvg PaidMarkup RatioGap per ServiceTotal PaymentsServicesBeneficiaries
2014$1.5K$825.441.76x$626.73$5.3M6.5K10
2015$2.0K$1.6K1.25x$390.88$8.8M5.5K7
2016$3.4K$3.1K1.08x$261.69$10.8M3.5K4
2017$3.2K$2.9K1.09x$264.86$4.7M1.6K3
2018$6.8K$3.5K1.91x$3.2K$8.2M2.3K2
2019$6.4K$3.7K1.72x$2.7K$12.4M3.3K3
2020$6.2K$3.7K1.65x$2.4K$13.6M3.6K4
2021$5.8K$3.8K1.52x$2.0K$26.1M6.8K4
2022$5.7K$3.8K1.51x$1.9K$32.3M8.6K3
2023$5.6K$3.8K1.50x$1.9K$38.4M10.2K3

Top Procedures (14)

81518Mrna gene analysis of 11 genes in breast tumor tissue
$99.0M
25.9K services$3.8K/svc1.42x markup
81540Gene analysis (cancer)
$36.8M
10.6K services$3.5K/svc1.87x markup
81479Molecular pathology procedure
$21.2M
6.6K services$3.2K/svc1.29x markup
84999Chemistry procedures
$2.4M
842 services$2.9K/svc1.75x markup
88368Microscopic genetic analysis of tissue
$397.6K
2.2K services$179.82/svc1.51x markup
81235Gene analysis (epidermal growth factor receptor), common variants
$251.2K
778 services$322.92/svc1.55x markup
81404Molecular pathology procedure level 5
$142.4K
1.5K services$92.27/svc1.17x markup
81275Gene analysis (v-Ki-ras2 Kirsten rat sarcoma viral oncogene) variants in codons 12 and 13
$134.9K
737 services$183.04/svc1.18x markup
81210Gene analysis (v-raf murine sarcoma viral oncogene homolog B1)
$126.7K
741 services$171.02/svc1.07x markup
88381Preparation of specimen, manual
$95.2K
875 services$108.80/svc1.82x markup
88369Microscopic genetic examination manualโš  4.3x markup
$38.2K
635 services$60.24/svc4.32x markup
G0462Immunohistochemistry or immunocytochemistry, per specimen; each additional single or multiplex antibody stain (list separately in addition to code for primary procedure)โš  3.2x markup
$15.9K
284 services$56.16/svc3.16x markup
88380Preparation of specimen using laser
$8.0K
89 services$89.35/svc2.24x markup
G0461Immunohistochemistry or immunocytochemistry, per specimen; first single or multiplex antibody stain
$7.9K
108 services$72.90/svc2.18x markup
Show detailed table โ–พ
CodeDescriptionServicesPaymentsAvg/ServiceMarkup
81518Mrna gene analysis of 11 genes in breast tumor tissue25.9K$99.0M$3.8K1.42x
81540Gene analysis (cancer)10.6K$36.8M$3.5K1.87x
81479Molecular pathology procedure6.6K$21.2M$3.2K1.29x
84999Chemistry procedures842$2.4M$2.9K1.75x
88368Microscopic genetic analysis of tissue2.2K$397.6K$179.821.51x
81235Gene analysis (epidermal growth factor receptor), common variants778$251.2K$322.921.55x
81404Molecular pathology procedure level 51.5K$142.4K$92.271.17x
81275Gene analysis (v-Ki-ras2 Kirsten rat sarcoma viral oncogene) variants in codons 12 and 13737$134.9K$183.041.18x
81210Gene analysis (v-raf murine sarcoma viral oncogene homolog B1)741$126.7K$171.021.07x
88381Preparation of specimen, manual875$95.2K$108.801.82x
88369Microscopic genetic examination manual635$38.2K$60.244.32x
G0462Immunohistochemistry or immunocytochemistry, per specimen; each additional single or multiplex antibody stain (list separately in addition to code for primary procedure)284$15.9K$56.163.16x
88380Preparation of specimen using laser89$8.0K$89.352.24x
G0461Immunohistochemistry or immunocytochemistry, per specimen; first single or multiplex antibody stain108$7.9K$72.902.18x

Markup Analysis

Charge-to-Payment Ratio

1.51x

This provider submits charges 1.51 times higher than what Medicare actually pays.

What This Means

A markup ratio of 1.51x means for every $100 Medicare pays, this provider initially charges $151. This is lower than the national average.

Location

San Diego, CA

Provider Verification

Always verify provider credentials and location before scheduling appointments. This data reflects Medicare payments and may not include all practice locations.

Similar Providers

Other Clinical Laboratory providers in CA for peer comparison.

Biotheranostics, Inc. (you)
$160.7M
Genomic Health, Inc.
$887.6M
Unilab Corporationโš ๏ธ
$868.8M
Caredx Inc.
$751.0M
Laboratory Corporation Of Americaโš ๏ธ
$592.4M
Millennium Health, Llc
$587.9M
Show detailed table โ–พ
ProviderLocationTotal PaymentsStatus
Genomic Health, Inc.Redwood City, CA$887.6Mโœ“ Clear
Unilab CorporationWest Hills, CA$868.8Mโš ๏ธ Flagged
Caredx Inc.Brisbane, CA$751.0Mโœ“ Clear
Laboratory Corporation Of AmericaSan Diego, CA$592.4Mโš ๏ธ Flagged
Millennium Health, LlcSan Diego, CA$587.9Mโœ“ Clear

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Data Sources

  • โ€ข Centers for Medicare & Medicaid Services (CMS)
  • โ€ข Medicare Provider Utilization and Payment Data (2014-2023)
  • โ€ข National Plan and Provider Enumeration System (NPPES)

Last Updated: February 2026 (data through 2023, the latest CMS release)

Note: All data is from publicly available Medicare records. OpenMedicare is an independent journalism project not affiliated with CMS.

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