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Data Sources: Centers for Medicare & Medicaid Services (CMS), Medicare Provider Utilization and Payment Data
Disclaimer: This site is an independent journalism project. Data analysis and editorial content are not affiliated with or endorsed by CMS or any government agency. All spending figures are based on publicly available Medicare payment records.
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ยฉ 2026 OpenMedicare. Independent data journalism. Built by TheDataProject.ai

Methodologyโ€ขDownload Data
  1. Home
  2. Providers
  3. Circulogene Theranostics Llc
๐Ÿ”ฌ
Organization

Circulogene Theranostics Llc

NPI: 1730558602
Homewood, AL
9 years of data
Clinical Laboratory
$15.6M
Total Payments
14.5K
Beneficiaries
15.9K
Services
2.26x
Markup Ratio

Peer Comparison

94th
percentile in specialty
This provider$15.6M
Specialty median$1.9M

๐Ÿ“‹ Key Findings

1Billed $15.6M over 9 years
22.26x markup ratio (above median)
394th percentile in Clinical Laboratory by payments
4Payments surged 20787% in 2016
56 procedures with >3x markup
โœ“ No flags detected

๐Ÿ”Ž Data Analysis

This provider's $15.6M in total Medicare payments ranks in the 94th percentile of Clinical Laboratory providers nationally.

Medicare payments to this provider grew 102156% from 2015 to 2023.

70% of their billing comes from a single procedure code (81455 โ€” Test for detecting genes associated with cancer).

AI-generated analysis based on Medicare payment data.

Annual Medicare Payments

Annual Services Provided

Avg Payment per Service

Markup Ratio Over Time

๐Ÿ“ˆ

Notable: Payments increased 20787% in 2016

Year-over-year payment surges can indicate changes in practice volume, new services, or billing pattern shifts.

Submitted Charges vs. Medicare Payments

Average per-service amounts submitted by the provider compared to what Medicare actually paid โ€” the gap represents the markup.

YearAvg SubmittedAvg PaidMarkup RatioGap per ServiceTotal PaymentsServicesBeneficiaries
2015$3.5K$88.2039.68x$3.4K$2.2K2521
2016$834.35$308.172.71x$526.18$460.5K1.6K965
2017$591.88$270.772.19x$321.11$202.6K722570
2018$2.0K$593.403.33x$1.4K$245.1K559543
2019$2.7K$554.064.88x$2.1K$445.8K1.0K1.0K
2020$3.4K$660.615.09x$2.7K$2.4M2.3K2.2K
2021$3.1K$887.923.45x$2.2K$3.9M3.1K2.9K
2022$2.0K$977.932.03x$1.0K$5.7M4.7K4.4K
2023$2.0K$970.632.04x$1.0K$2.3M1.9K1.8K

Top Procedures (20)

81455Test for detecting genes associated with cancer
$10.9M
3.8K services$2.9K/svc2.04x markup
81194Gene analysis (neurotrophic receptor tyrosine kinase 1, 2, and 3) translocation analysis
$1.6M
3.1K services$512.82/svc2.15x markup
81301Microsatellite instability analysis
$1.4M
4.0K services$345.23/svc2.41x markup
81162Gene analysis (breast cancer 1 and 2) full sequence and duplication or deletion variants
$258.5K
127 services$2.0K/svc2.88x markup
81445Test for detecting genes associated with cancer of body organโš  6.7x markup
$257.7K
459 services$561.39/svc6.68x markup
81436Test for detecting genes associated with colon cancerโš  4.3x markup
$218.4K
376 services$580.84/svc4.26x markup
81479Molecular pathology procedureโš  5.1x markup
$195.3K
922 services$211.86/svc5.14x markup
81404Molecular pathology procedure level 5
$130.2K
445 services$292.66/svc1.03x markup
81235Gene analysis (epidermal growth factor receptor), common variants
$119.2K
381 services$312.93/svc2.34x markup
81275Gene analysis (v-Ki-ras2 Kirsten rat sarcoma viral oncogene) variants in codons 12 and 13
$109.3K
568 services$192.51/svc2.19x markup
81210Gene analysis (v-raf murine sarcoma viral oncogene homolog B1)
$95.9K
552 services$173.72/svc2.50x markup
81405Molecular pathology procedure level 6
$78.8K
269 services$293.03/svc1.02x markup
81321Gene analysis (phosphatase and tensin homolog), full sequence analysis
$77.0K
261 services$295.13/svc1.03x markup
81435Test for detecting genes associated with colon cancerโš  5.5x markup
$74.1K
125 services$592.51/svc5.51x markup
81432Test for detecting genes associated with inherited breast cancer-related disordersโš  5.7x markup
$56.0K
75 services$746.18/svc5.68x markup
81406Molecular pathology procedure level 7
$39.1K
133 services$294.00/svc1.02x markup
81311Gene analysis for cancer (neuroblastoma)
$30.5K
106 services$287.90/svc1.04x markup
81403Molecular pathology procedure level 4
$13.6K
59 services$230.30/svc1.30x markup
81450Test for detecting genes associated with blood related cancerโš  5.5x markup
$11.4K
18 services$635.43/svc5.51x markup
81201Gene analysis (adenomatous polyposis coli), full gene sequence
$9.2K
76 services$120.54/svc2.49x markup
Show detailed table โ–พ
CodeDescriptionServicesPaymentsAvg/ServiceMarkup
81455Test for detecting genes associated with cancer3.8K$10.9M$2.9K2.04x
81194Gene analysis (neurotrophic receptor tyrosine kinase 1, 2, and 3) translocation analysis3.1K$1.6M$512.822.15x
81301Microsatellite instability analysis4.0K$1.4M$345.232.41x
81162Gene analysis (breast cancer 1 and 2) full sequence and duplication or deletion variants127$258.5K$2.0K2.88x
81445Test for detecting genes associated with cancer of body organ459$257.7K$561.396.68x
81436Test for detecting genes associated with colon cancer376$218.4K$580.844.26x
81479Molecular pathology procedure922$195.3K$211.865.14x
81404Molecular pathology procedure level 5445$130.2K$292.661.03x
81235Gene analysis (epidermal growth factor receptor), common variants381$119.2K$312.932.34x
81275Gene analysis (v-Ki-ras2 Kirsten rat sarcoma viral oncogene) variants in codons 12 and 13568$109.3K$192.512.19x
81210Gene analysis (v-raf murine sarcoma viral oncogene homolog B1)552$95.9K$173.722.50x
81405Molecular pathology procedure level 6269$78.8K$293.031.02x
81321Gene analysis (phosphatase and tensin homolog), full sequence analysis261$77.0K$295.131.03x
81435Test for detecting genes associated with colon cancer125$74.1K$592.515.51x
81432Test for detecting genes associated with inherited breast cancer-related disorders75$56.0K$746.185.68x
81406Molecular pathology procedure level 7133$39.1K$294.001.02x
81311Gene analysis for cancer (neuroblastoma)106$30.5K$287.901.04x
81403Molecular pathology procedure level 459$13.6K$230.301.30x
81450Test for detecting genes associated with blood related cancer18$11.4K$635.435.51x
81201Gene analysis (adenomatous polyposis coli), full gene sequence76$9.2K$120.542.49x

Markup Analysis

Charge-to-Payment Ratio

2.26x

This provider submits charges 2.26 times higher than what Medicare actually pays.

What This Means

A markup ratio of 2.26x means for every $100 Medicare pays, this provider initially charges $226. This is higher than the national average.

Location

Homewood, AL

Provider Verification

Always verify provider credentials and location before scheduling appointments. This data reflects Medicare payments and may not include all practice locations.

Similar Providers

Other Clinical Laboratory providers in AL for peer comparison.

Circulogene Theranostics Llc (you)
$15.6M
Laboratory Corporation Of America Holdingsโš ๏ธ
$692.7M
Eurofins Diatherix Laboratories Llc
$37.8M
Show detailed table โ–พ
ProviderLocationTotal PaymentsStatus
Laboratory Corporation Of America HoldingsBirmingham, AL$692.7Mโš ๏ธ Flagged
Eurofins Diatherix Laboratories LlcHuntsville, AL$37.8Mโœ“ Clear

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Data Sources

  • โ€ข Centers for Medicare & Medicaid Services (CMS)
  • โ€ข Medicare Provider Utilization and Payment Data (2014-2023)
  • โ€ข National Plan and Provider Enumeration System (NPPES)

Last Updated: February 2026 (data through 2023, the latest CMS release)

Note: All data is from publicly available Medicare records. OpenMedicare is an independent journalism project not affiliated with CMS.

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