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Data Sources: Centers for Medicare & Medicaid Services (CMS), Medicare Provider Utilization and Payment Data
Disclaimer: This site is an independent journalism project. Data analysis and editorial content are not affiliated with or endorsed by CMS or any government agency. All spending figures are based on publicly available Medicare payment records.
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ยฉ 2026 OpenMedicare. Independent data journalism. Built by TheDataProject.ai

Methodologyโ€ขDownload Data
  1. Home
  2. Providers
  3. Esoterix, Inc
๐Ÿ”ฌ
Organization

Esoterix, Inc

NPI: 1962489237
Calabasas Hills, CA
10 years of data
Clinical Laboratory
$32.5M
Total Payments
650
Beneficiaries
403.9K
Services
2.74x
Markup Ratio

Peer Comparison

97th
percentile in specialty
This provider$32.5M
Specialty median$1.9M

๐Ÿ“‹ Key Findings

1Billed $32.5M over 10 years
22.74x markup ratio (above median)
3Risk score: 68 โ€” flagged for review
497th percentile in Clinical Laboratory by payments
5Payments surged 730% in 2021
618 procedures with >3x markup

โš ๏ธ Flagged for Review

Risk Score: 68
  • 99x specialty median spending
  • Markup 8.8x (specialty median: 2.5x)
  • 41x specialty median beneficiaries
  • 28x specialty median services
View Deep Dives โ†’Report Fraud โ†’

Statistical flag only โ€” not an accusation of fraud

๐Ÿ”Ž Data Analysis

This provider's $32.5M in total Medicare payments ranks in the 97th percentile of Clinical Laboratory providers nationally.

Medicare payments to this provider grew 1410% from 2014 to 2023.

81% of their billing comes from a single procedure code (81490 โ€” Test for detecting genes associated with rheumatoid arthritis using immunoassay technique).

This provider has been statistically flagged with a risk score of 68/100. Statistical flags are not accusations of fraud.

AI-generated analysis based on Medicare payment data.

Annual Medicare Payments

Annual Services Provided

Avg Payment per Service

Markup Ratio Over Time

๐Ÿ“ˆ

Notable: Payments increased 730% in 2021

Year-over-year payment surges can indicate changes in practice volume, new services, or billing pattern shifts.

Submitted Charges vs. Medicare Payments

Average per-service amounts submitted by the provider compared to what Medicare actually paid โ€” the gap represents the markup.

YearAvg SubmittedAvg PaidMarkup RatioGap per ServiceTotal PaymentsServicesBeneficiaries
2014$176.59$28.036.30x$148.56$681.0K24.3K59
2015$174.99$27.006.48x$147.99$763.6K28.3K62
2016$175.21$28.166.22x$147.05$717.6K25.5K57
2017$172.61$27.666.24x$144.95$616.5K22.3K58
2018$167.55$24.656.80x$142.90$543.5K22.1K56
2019$167.74$21.837.68x$145.91$547.2K25.1K57
2020$157.48$19.588.04x$137.90$671.6K34.3K71
2021$230.50$96.812.38x$133.69$5.6M57.6K73
2022$300.99$164.661.83x$136.33$12.2M73.8K78
2023$251.05$113.342.22x$137.71$10.3M90.7K79

Top Procedures (20)

81490Test for detecting genes associated with rheumatoid arthritis using immunoassay technique
$24.6M
29.7K services$829.99/svc1.19x markup
82306Vitamin d-3 levelโš  9.0x markup
$1.2M
32.5K services$35.88/svc9.03x markup
86235Measurement of antibody for assessment of autoimmune disorder, any methodโš  7.6x markup
$788.5K
44.5K services$17.72/svc7.63x markup
82533Cortisol (hormone) measurement, totalโš  4.4x markup
$569.1K
30.9K services$18.43/svc4.39x markup
82523Collagen cross links test, (urine test to evaluate bone health)โš  8.8x markup
$404.0K
19.4K services$20.81/svc8.75x markup
84403Testosterone (hormone) level, totalโš  5.7x markup
$374.7K
12.2K services$30.68/svc5.65x markup
82397Analysis using chemiluminescent technique (light and chemical )reactionโš  11.4x markup
$302.1K
19.5K services$15.51/svc11.43x markup
86147Cardiolipin antibody (tissue antibody) measurementโš  6.7x markup
$274.3K
10.9K services$25.14/svc6.66x markup
84402Testosterone (hormone) level, freeโš  5.6x markup
$268.3K
9.0K services$29.83/svc5.57x markup
84432Thyroglobulin (thyroid related hormone) levelโš  6.0x markup
$215.1K
11.6K services$18.61/svc5.97x markup
83970Parathormone (parathyroid hormone) levelโš  3.3x markup
$211.0K
4.3K services$48.74/svc3.31x markup
83520Measurement of substance using immunoassay techniqueโš  9.7x markup
$200.6K
11.7K services$17.09/svc9.74x markup
86800Thyroglobulin (thyroid protein) antibody measurementโš  5.7x markup
$184.8K
10.0K services$18.45/svc5.65x markup
G0480Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms
$179.5K
1.9K services$95.30/svc2.05x markup
84140Pregnenolone (reproductive hormone) levelโš  5.3x markup
$139.5K
5.8K services$24.18/svc5.33x markup
84443Blood test, thyroid stimulating hormone (tsh)โš  6.4x markup
$130.8K
6.7K services$19.59/svc6.40x markup
80299Quantitation of therapeutic drugโš  12.8x markup
$122.3K
6.7K services$18.37/svc12.81x markup
86160Measurement of complement (immune system proteins), antigen,โš  7.0x markup
$119.0K
10.0K services$11.86/svc6.98x markup
83516Analysis of substance using immunoassay technique, multiple step methodโš  14.3x markup
$105.7K
9.3K services$11.34/svc14.32x markup
84270Sex hormone binding globulin (protein) levelโš  6.0x markup
$105.4K
4.1K services$25.59/svc6.03x markup
Show detailed table โ–พ
CodeDescriptionServicesPaymentsAvg/ServiceMarkup
81490Test for detecting genes associated with rheumatoid arthritis using immunoassay technique29.7K$24.6M$829.991.19x
82306Vitamin d-3 level32.5K$1.2M$35.889.03x
86235Measurement of antibody for assessment of autoimmune disorder, any method44.5K$788.5K$17.727.63x
82533Cortisol (hormone) measurement, total30.9K$569.1K$18.434.39x
82523Collagen cross links test, (urine test to evaluate bone health)19.4K$404.0K$20.818.75x
84403Testosterone (hormone) level, total12.2K$374.7K$30.685.65x
82397Analysis using chemiluminescent technique (light and chemical )reaction19.5K$302.1K$15.5111.43x
86147Cardiolipin antibody (tissue antibody) measurement10.9K$274.3K$25.146.66x
84402Testosterone (hormone) level, free9.0K$268.3K$29.835.57x
84432Thyroglobulin (thyroid related hormone) level11.6K$215.1K$18.615.97x
83970Parathormone (parathyroid hormone) level4.3K$211.0K$48.743.31x
83520Measurement of substance using immunoassay technique11.7K$200.6K$17.099.74x
86800Thyroglobulin (thyroid protein) antibody measurement10.0K$184.8K$18.455.65x
G0480Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms1.9K$179.5K$95.302.05x
84140Pregnenolone (reproductive hormone) level5.8K$139.5K$24.185.33x
84443Blood test, thyroid stimulating hormone (tsh)6.7K$130.8K$19.596.40x
80299Quantitation of therapeutic drug6.7K$122.3K$18.3712.81x
86160Measurement of complement (immune system proteins), antigen,10.0K$119.0K$11.866.98x
83516Analysis of substance using immunoassay technique, multiple step method9.3K$105.7K$11.3414.32x
84270Sex hormone binding globulin (protein) level4.1K$105.4K$25.596.03x

Markup Analysis

Charge-to-Payment Ratio

2.74x

This provider submits charges 2.74 times higher than what Medicare actually pays.

What This Means

A markup ratio of 2.74x means for every $100 Medicare pays, this provider initially charges $274. This is higher than the national average.

Location

Calabasas Hills, CA

Provider Verification

Always verify provider credentials and location before scheduling appointments. This data reflects Medicare payments and may not include all practice locations.

Similar Providers

Other Clinical Laboratory providers in CA for peer comparison.

Esoterix, Inc (you)
$32.5M
Genomic Health, Inc.
$887.6M
Unilab Corporationโš ๏ธ
$868.8M
Caredx Inc.
$751.0M
Laboratory Corporation Of Americaโš ๏ธ
$592.4M
Millennium Health, Llc
$587.9M
Show detailed table โ–พ
ProviderLocationTotal PaymentsStatus
Genomic Health, Inc.Redwood City, CA$887.6Mโœ“ Clear
Unilab CorporationWest Hills, CA$868.8Mโš ๏ธ Flagged
Caredx Inc.Brisbane, CA$751.0Mโœ“ Clear
Laboratory Corporation Of AmericaSan Diego, CA$592.4Mโš ๏ธ Flagged
Millennium Health, LlcSan Diego, CA$587.9Mโœ“ Clear

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Data Sources

  • โ€ข Centers for Medicare & Medicaid Services (CMS)
  • โ€ข Medicare Provider Utilization and Payment Data (2014-2023)
  • โ€ข National Plan and Provider Enumeration System (NPPES)

Last Updated: February 2026 (data through 2023, the latest CMS release)

Note: All data is from publicly available Medicare records. OpenMedicare is an independent journalism project not affiliated with CMS.

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