How Much Does Gene analysis (colorectal cancer) Cost on Medicare?

Cost analysis for CPT 81528 — Gene analysis (colorectal cancer)

Average Medicare Payment

N/A

Total Payments (Latest)

N/A

Services (Latest)

N/A

Price Change (–)

N/A

🗺️ State-by-State Cost Variation

The most expensive state pays 1.0x more than the cheapest for this procedure. MN averages $498.69 vs WI at $498.52.

State	Avg Payment	Total Payments	Services	Providers
MN	$498.69	$1.5M	2.9K	2
FL	$498.69	$154.6K	310	1
WI	$498.52	$299.3M	600.4K	1

💰 Who Bills the Most for This Procedure?

Provider	Specialty	State	Payments	Services	Avg/Service
Exact Sciences Laboratories, Llc	Clinical Laboratory	WI	$299.3M	600.4K	$498.52
Mayo Collaborative Services, Inc	Clinical Laboratory	MN	$929.1K	1.9K	$498.69
Mayo Clinic	Clinical Laboratory	MN	$525.6K	1.1K	$498.69
Mayo Clinic Jacksonville	Clinical Laboratory	FL	$154.6K	310	$498.69

🤔 Is Gene analysis (colorectal cancer) Overpriced?

Based on the data, CPT 81528 shows a 1.0x variation in pricing across states — relatively consistent by Medicare standards.

Medicare's fee schedule attempts to standardize pricing, though some variation is expected due to geographic cost-of-living adjustments and practice expense differences.

This analysis is based on publicly available CMS data and does not account for patient complexity, comorbidities, or facility-specific factors that may justify pricing differences.

Data Sources

• Centers for Medicare & Medicaid Services (CMS)
• Medicare Provider Utilization and Payment Data (2014-2023)
• Medicare Physician Fee Schedule

Note: All data is from publicly available Medicare records. OpenMedicare is an independent journalism project not affiliated with CMS.