How Much Does Gene analysis of prostate tumor tissue, profiling by real-time rt-pcr of 46 genes Cost on Medicare?

Cost analysis for CPT 81541 — Gene analysis of prostate tumor tissue, profiling by real-time rt-pcr of 46 genes

Average Medicare Payment

$3776.86

2023 data

Total Payments (2023)

$32.6M

Services (2023)

8.6K

Price Change (2018–2023)

-0.3%

📈 Year-over-Year Cost Trend

Year	Avg Payment	Total Payments	Services	YoY Change
2018	$3789.67	$15.7M	4.1K	—
2019	$3789.68	$16.1M	4.2K	+0.0%
2020	$3838.76	$21.0M	5.5K	+1.3%
2021	$3861.56	$28.9M	7.5K	+0.6%
2022	$3811.92	$30.9M	8.1K	-1.3%
2023	$3776.86	$32.6M	8.6K	-0.9%

🗺️ State-by-State Cost Variation

The most expensive state pays 1.0x more than the cheapest for this procedure. UT averages $3776.86 vs UT at $3776.86.

State	Avg Payment	Total Payments	Services	Providers
UT	$3776.86	$32.6M	8.6K	1

💰 Who Bills the Most for This Procedure?

Provider	Specialty	State	Payments	Services	Avg/Service
Myriad Genetic Laboratories, Inc.	Clinical Laboratory	UT	$32.6M	8.6K	$3776.86

🤔 Is Gene analysis of prostate tumor tissue, profiling by real-time rt-pcr of 46 genes Overpriced?

Based on the data, CPT 81541 shows a 1.0x variation in pricing across states — relatively consistent by Medicare standards.

Costs have decreased 0.3% since 2018. Medicare's fee schedule attempts to standardize pricing, though some variation is expected due to geographic cost-of-living adjustments and practice expense differences.

This analysis is based on publicly available CMS data and does not account for patient complexity, comorbidities, or facility-specific factors that may justify pricing differences.

Data Sources

• Centers for Medicare & Medicaid Services (CMS)
• Medicare Provider Utilization and Payment Data (2014-2023)
• Medicare Physician Fee Schedule

Note: All data is from publicly available Medicare records. OpenMedicare is an independent journalism project not affiliated with CMS.