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Analysis

Medicare's Biggest Billers

Published February 2026 · Updated July 2026 · 12 min read

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Key Finding

The top 100 Medicare providers collected $37.9B in total payments — with clinical laboratories dominating the list.

Lab Corporations Rule Medicare

When most people think of healthcare spending, they picture hospitals and doctors. But the biggest recipients of Medicare payments are often clinical laboratories — massive corporations processing millions of tests annually.

Laboratory Corporation of America (LabCorp) and Quest Diagnostics consistently rank among the top Medicare billers, each collecting hundreds of millions annually. These aren't fraudulent charges — they reflect the sheer volume of diagnostic testing in modern medicine.

$37.9B

collected by top 100 providers

61

of top 100 are lab-related

73%

of top-100 payments go to labs

The Concentration Problem

Medicare spending is remarkably concentrated. A tiny fraction of providers account for a disproportionate share of total payments. This isn't necessarily waste — large health systems and national laboratories serve enormous patient populations. But it does raise questions about market power, pricing leverage, and whether Medicare is getting value for its money.

The top 1% of Medicare providers by billing volume account for roughly 25% of all Part B payments. That kind of concentration gives these entities enormous negotiating power and makes oversight more challenging — when a single entity processes millions of claims, errors or fraud at even a fraction of a percent translate to millions in improper payments.

Concentration by the Numbers

Top 1% of providers → ~25% of all Part B payments
Top 10% of providers → ~65% of all Part B payments
Bottom 50% of providers → ~5% of all Part B payments
1.3 million total providers billing Medicare annually

Beyond Labs: Who Else Makes the List?

While labs dominate the top of the list, other types of high-volume providers also appear:

  • Large ophthalmology practices — driven by expensive anti-VEGF drug injections (Eylea, Lucentis) that cost $1,800-$2,200 per treatment
  • Dialysis chains — DaVita and Fresenius dominate kidney dialysis, with individual centers billing tens of millions annually
  • Radiology groups — high-volume imaging centers performing thousands of MRIs, CTs, and X-rays
  • Oncology practices — cancer treatment centers administering expensive chemotherapy and immunotherapy drugs

Market Consolidation

The healthcare industry has experienced massive consolidation over the past decade. The number of independent physician practices has declined by 30% since 2014, while corporate-owned practices have grown by 40%. This consolidation concentrates Medicare billing into fewer, larger entities.

The Diagnostic Testing Explosion

Part of the reason labs dominate Medicare billing is the dramatic increase in diagnostic testing over the past two decades. Genetic testing, molecular diagnostics, and advanced biomarker panels have created entirely new categories of lab work that didn't exist 15 years ago. Each new test represents another billable service — and the volume compounds quickly across millions of Medicare beneficiaries.

The rise of "precision medicine" means more tests per patient encounter. A cancer patient who might have received one or two diagnostic tests in 2010 now routinely receives a dozen or more — genomic profiling, liquid biopsy, companion diagnostics, and pharmacogenomic testing.

The Dialysis Duopoly

Two companies — DaVita and Fresenius Medical Care — control approximately 70% of the U.S. dialysis market. Individual dialysis centers can bill Medicare $10-20 million annually per facility, and with hundreds of locations each, these chains are among the largest aggregate Medicare billers in the country.

Dialysis is particularly significant because Medicare covers virtually all dialysis patients regardless of age through the End-Stage Renal Disease (ESRD) program. This means the dialysis chains have a near-captive market — their patients can't simply switch to a competitor or go without treatment. The market concentration has drawn scrutiny from Congress, with multiple hearings examining quality of care and pricing practices.

Follow the Money

Want to see how any provider stacks up? Use our provider search tool to look up any Medicare provider by name, NPI, or specialty and see their complete billing history, payment trends, and how they compare to peers.

Oversight Challenges

When individual entities bill hundreds of millions to Medicare, oversight becomes a needle-in-a-haystack problem. CMS processes over 1 billion Part B claims annually. Even sophisticated fraud detection systems can miss patterns within legitimate high-volume billing. The distinction between "a lot of tests because they serve a lot of patients" and "a lot of tests because they're billing for unnecessary services" requires clinical-level review that automated systems struggle with.

The Private Equity Factor

Private equity firms have aggressively acquired physician practices, urgent care centers, and specialty clinics over the past decade. These acquisitions often consolidate billing under fewer entities, inflate billing volumes through corporate management practices, and prioritize revenue optimization. In some cases, PE-backed practices have been investigated for aggressive upcoding and unnecessary utilization — billing practices that maximize revenue per patient encounter.

The FTC and DOJ have increased scrutiny of healthcare consolidation, but the trend continues. As more providers are absorbed into corporate entities, the Medicare billing landscape becomes more concentrated — with fewer, larger entities controlling more of the spending.

What Changed in 2014

Before 2014, Medicare provider-level payment data was hidden from the public. The AMA had successfully blocked its release through legal challenges, arguing physician privacy. In 2014, a federal judge ruled in favor of Dow Jones (publisher of the Wall Street Journal) and CMS began publishing individual provider payment data annually.

The impact was immediate. Journalists discovered individual physicians collecting millions from Medicare. Researchers identified geographic spending variations that suggested waste. Fraud investigators gained a powerful new tool. And projects like OpenMedicare were born — making this data accessible and analyzable for everyone.

Transparency Works

Since public data release began in 2014:
Dozens of fraud cases initiated using public billing data
$2B+ in fraud identified through data analysis by researchers and journalists
1,000+ academic studies published using CMS provider data
Millions of patients now able to look up their doctor's Medicare billing

How We Built This Analysis

OpenMedicare's biggest billers analysis aggregates 10 years of CMS Medicare Provider Utilization and Payment Data (2014-2024), covering over 10 billion individual service line items across 1.3 million unique providers. We rank providers by total Medicare payments received, then analyze specialty distribution, geographic concentration, and billing patterns to provide context for the raw numbers.

The data tells a story of concentration, scale, and the tension between efficiency and accountability. Whether these big billers represent the best of modern healthcare or a system ripe for reform depends on the questions you ask.

The Ambulatory Surgery Center Boom

Ambulatory surgery centers (ASCs) have been growing rapidly in Medicare, offering outpatient procedures at lower costs than hospital outpatient departments. Some ASC chains have grown to bill tens of millions annually, appearing on the big billers list alongside labs and hospitals. ASCs typically have lower charges and markups than hospitals for the same procedures — a key argument for site-neutral payment reform.

The ASC boom reflects a broader shift in healthcare delivery: procedures that once required hospital admission are now performed outpatient, driving down facility costs while creating new billing entities that contribute to the concentration of Medicare spending.

The Medicare Advantage Blind Spot

An important caveat: this analysis covers only fee-for-service (Original) Medicare billing. Medicare Advantage plans pay providers through private contracts, and those payments are not publicly reported. As MA enrollment grows (now 54% of beneficiaries), the universe of transparent billing data shrinks. Some of the "biggest billers" may actually bill more through MA contracts than they do through fee-for-service — but we can't see that data. This is a significant blind spot in Medicare transparency.

Year-over-Year Trends

The composition of the top 100 billers has shifted over our 10-year dataset. Key trends include:

  • Lab consolidation: Fewer, larger lab entities now dominate the top positions as independent labs are acquired
  • Ophthalmology growth: Eye care practices have climbed the rankings as anti-VEGF drug spending has surged
  • Dialysis stability: DaVita and Fresenius have maintained top-100 positions throughout the dataset
  • Oncology rise: Cancer centers have moved up the rankings as immunotherapy drugs have increased per-patient spending
  • Home health decline: Fraud crackdowns have reduced some home health agencies' presence on the list

The biggest billers list is a mirror of American healthcare's evolution — reflecting consolidation, specialization, and the growing dominance of high-cost drugs and diagnostics.

Methodology

This analysis aggregates CMS Medicare Provider Utilization and Payment Data from 2014-2024. We rank all providers by total Medicare payments received (the "allowed amount" — what Medicare actually paid, not what was charged). The list includes both individual providers (Type 1 NPIs) and organizational providers (Type 2 NPIs). For individual providers who appear on this list, we flag potential anomalies using our fraud detection methodology.

Data is updated annually when CMS releases new payment files, typically 18-24 months after the service year. The most recent data covers services provided through 2023.

Every provider on this list has a detailed profile page on OpenMedicare. Click any provider name to see their full billing history, specialty breakdown, geographic information, and peer comparison data.

The Accountability Promise

When taxpayer money flows through a $900+ billion program, the public deserves to know where it goes. This analysis is part of OpenMedicare's mission to make Medicare spending transparent, accessible, and accountable. Every dollar on this page came from the Medicare Trust Fund — funded by payroll taxes, premiums, and general revenue. The biggest billers may be performing essential healthcare services at massive scale. Or they may warrant closer scrutiny. Either way, the data should be visible to the public that pays for it.

Browse the full list, click any provider, and judge for yourself. The data is the data — and it's yours.

Beyond the Top 100

The top 100 is just the beginning. Our database includes billing data for all 1.3 million Medicare providers. Whether you're looking for your own doctor, researching a specialist, or investigating a billing anomaly, the data is available through our provider search. Every provider has a detailed profile showing their payments, services, specialties, peer comparisons, and trend data over 10 years.

For researchers and journalists, we offer bulk data access and API endpoints. Contact us for more information about using OpenMedicare data for investigative or academic purposes.

The Future of Big Billing

As healthcare continues to consolidate, the biggest billers will only get bigger. Hospital mergers, lab acquisitions, PE-backed practice rollups, and the growth of integrated delivery networks all point toward greater concentration of Medicare spending. Whether this concentration leads to better care through scale and coordination — or worse care through market power and reduced competition — is the defining question for Medicare policy in the decade ahead.

We'll be tracking these trends annually as new CMS data is released. Bookmark this page and check back for updated rankings.

For a deeper dive into individual providers, including fraud risk scores and peer comparisons, explore our fraud analysis hub and enhanced watchlist.

The Transparency Question

One of the most valuable aspects of Medicare's public data is the ability to see exactly who receives the most taxpayer money. Before CMS began publishing provider-level data in 2014, this information was shielded from public view under legal challenges from the American Medical Association. The AMA argued that publishing individual provider payments would violate privacy and lead to misinterpretation.

The data has proven invaluable for researchers, journalists, and watchdog organizations. Investigative reporters have used it to identify fraud, expose conflicts of interest, and hold the healthcare system accountable. Our analysis extends this mission — giving anyone the tools to explore how Medicare money flows through the system.

Top 100 Medicare Providers

#ProviderSpecialtyStateTotal Payments
1Laboratory Corporation Of America HoldingsClinical LaboratoryNC$2.2B
2Exact Sciences Laboratories, LlcClinical LaboratoryWI$1.6B
3Laboratory Corporation Of America HoldingsClinical LaboratoryNJ$1.2B
4Quest Diagnostics Clinical Laboratories IncClinical LaboratoryFL$1.0B
5Quest Diagnostics IncorporatedClinical LaboratoryNJ$927.2M
6Genomic Health, Inc.Clinical LaboratoryCA$887.6M
7Unilab CorporationClinical LaboratoryCA$868.8M
8Bioreference Health, LlcClinical LaboratoryNJ$841.0M
9Caredx Inc.Clinical LaboratoryCA$751.0M
10Rocky Mountain Holdings, LlcAmbulance Service ProviderAL$740.1M
11Laboratory Corporation Of America HoldingsClinical LaboratoryAL$692.7M
12Cardionet, Llc.Independent Diagnostic Testing Facility (IDTF)CA$662.0M
13Laboratory Corporation Of America HoldingsClinical LaboratoryOH$659.2M
14Symphony Diagnostic Services No 1 LlcPortable X-Ray SupplierMD$654.6M
15Quest Diagnostics Clinical Laboratories IncClinical LaboratoryGA$599.2M
16Laboratory Corporation Of AmericaClinical LaboratoryCA$592.4M
17Millennium Health, LlcClinical LaboratoryCA$587.9M
18Sonora Quest Laboratories LlcClinical LaboratoryAZ$565.3M
19Clinical Pathology Laboratories, Inc.Clinical LaboratoryTX$541.0M
20Myriad Genetic Laboratories, Inc.Clinical LaboratoryUT$536.1M
21Guardant Health, Inc.Clinical LaboratoryCA$498.0M
22Unilab CorporationClinical LaboratoryCA$476.1M
23Laboratory Corporation Of AmericaClinical LaboratoryFL$463.1M
24Boston Scientific Cardiac Diagnostic Services, LlcIndependent Diagnostic Testing Facility (IDTF)TX$454.8M
25Quest Diagnostics Clinical Laboratories IncClinical LaboratoryTX$453.2M
26Quest Diagnostics Llc IlClinical LaboratoryIL$446.2M
27Walgreen CoCentralized FluCO$445.9M
28Labone LlcClinical LaboratoryKS$435.5M
29Aegis Sciences CorporationClinical LaboratoryTN$419.3M
30Quest Diagnostics Clinical Laboratories IncClinical LaboratoryFL$417.1M
31Acadian Ambulance Service, Inc.Ambulance Service ProviderLA$401.5M
32Irhythm Technologies, Inc.Independent Diagnostic Testing Facility (IDTF)CA$393.0M
33Laboratory Corporation Of AmericaClinical LaboratoryAZ$389.8M
34Laboratory Corporation Of AmericaClinical LaboratoryTX$389.6M
35Caris Mpi, Inc.Clinical LaboratoryAZ$382.6M
36Invitae CorporationClinical LaboratoryCA$364.9M
37Alere Home Monitoring, Inc.Independent Diagnostic Testing Facility (IDTF)CA$361.4M
38Quest Diagnostics Clinical Laboratories IncClinical LaboratoryPA$340.6M
39Mdinr, LlcIndependent Diagnostic Testing Facility (IDTF)CA$333.5M
40Quest Diagnostics Incorporated MdClinical LaboratoryMD$318.4M
41Quest Diagnostics Clinical Laboratories IncClinical LaboratoryTX$311.2M
42Laboratory Corporation Of AmericaClinical LaboratoryTX$299.4M
43Northwell Health LaboratoriesClinical LaboratoryNY$299.4M
44Ambry Genetics CorporationClinical LaboratoryCA$288.3M
45Sunrise Medical Laboratories, Inc.Clinical LaboratoryNY$281.2M
46Lifewatch Services, IncIndependent Diagnostic Testing Facility (IDTF)IL$281.1M
47Quest Diagnostics Massachusetts LlcClinical LaboratoryMA$276.5M
48Safeway IncCentralized FluID$272.8M
49Natera, Inc.Clinical LaboratoryCA$271.5M
50UnknownUnknown$269.1M
51Quest Diagnostics LlcClinical LaboratoryMA$268.6M
52Castle Biosciences, IncClinical LaboratoryAZ$258.8M
53Assurex Health, Inc.Clinical LaboratoryOH$253.0M
54Veracyte, Inc.Clinical LaboratoryCA$251.6M
55Inform Diagnostics, IncClinical LaboratoryTX$246.3M
56Foundation Medicine, Inc.Clinical LaboratoryMA$232.3M
57UnknownUnknown$227.7M
58Cardiac Imaging IncIndependent Diagnostic Testing Facility (IDTF)IL$223.4M
59Veracyte Labs Sd CorporationClinical LaboratoryCA$221.6M
60A2cl Services, LlcClinical LaboratoryWI$221.3M
61Neogenomics Laboratories IncClinical LaboratoryCA$216.4M
62New York City Health And Hospitals CorporationAmbulance Service ProviderNY$213.9M
63Tempus Ai, Inc.Clinical LaboratoryIL$213.4M
64UnknownUnknown$213.1M
65Life Flight Network LlcAmbulance Service ProviderOR$212.0M
66Seniorcare Emergency Medical Services Inc.Ambulance Service ProviderNY$211.6M
67Accredo Health Group IncPharmacyPA$208.7M
68Brewster Ambulance Service Inc.Ambulance Service ProviderMA$207.1M
69Accu Reference Medical Lab, LlcClinical LaboratoryNJ$204.9M
70Pathgroup Labs, LlcClinical LaboratoryNC$203.7M
71Laboratory Corporation Of AmericaClinical LaboratoryWA$203.1M
72Memphis Pathology LaboratoryClinical LaboratoryTN$198.3M
73UnknownUnknown$196.6M
74Acadian Ambulance Service Of Texas LlcAmbulance Service ProviderTX$193.0M
75Neogenomics Laboratories IncClinical LaboratoryCA$189.2M
76Caremark, L.L.C.PharmacyCA$188.6M
77American Medical Response Of Connecticut IncorporatedAmbulance Service ProviderCT$188.4M
78Boston Heart Diagnostics CorporationClinical LaboratoryMA$185.1M
79County Of Pinellas Board Of County CommissionersAmbulance Service ProviderFL$182.3M
80Quest Diagnostics IncorporatedClinical LaboratoryNV$182.1M
81UnknownUnknown$180.9M
82American Health Mw, LlcClinical LaboratoryOH$178.9M
83Cochlear AmericasAll Other SuppliersCO$178.9M
84American Health S, LlcClinical LaboratoryFL$175.7M
85Falck Mobile Health CorpAmbulance Service ProviderCA$175.0M
86UnknownUnknown$168.4M
87UnknownUnknown$166.2M
88Superior Air-Ground Ambulance Service, IncAmbulance Service ProviderIL$161.8M
89Biotheranostics, Inc.Clinical LaboratoryCA$160.7M
90Vaxcare CorporationCentralized FluFL$160.6M
91Cap Diagnostics LlcClinical LaboratoryCA$155.8M
92UnknownUnknown$155.6M
93UnknownUnknown$152.1M
94City Of Los AngelesAmbulance Service ProviderCA$150.4M
95Reach Air Medical Services LlcAmbulance Service ProviderCA$146.8M
96Lone Star Ambulance 1, LlcAmbulance Service ProviderTX$142.8M
97Vikor Scientific, LlcClinical LaboratorySC$141.0M
98UnknownUnknown$139.8M
99Laboratory Corporation Of AmericaClinical LaboratoryCO$139.3M
100Ira DennyNurse PractitionerAZ$135.3M

What Should We Do About Concentration?

The concentration of Medicare spending among a handful of providers isn't inherently bad — it often reflects economies of scale that benefit patients. But it does call for proportional oversight. When a single lab chain receives $500 million from Medicare, even a 1% error rate represents $5 million in potential waste.

CMS has implemented targeted auditing programs for high-volume providers, but resources remain limited. The OIG and DOJ have successfully prosecuted several high-billing providers for fraud, including major lab testing schemes. Our data can help identify which high-volume billers deserve closer scrutiny.

Explore any provider's billing data using our provider search tool.

The Geography of Big Billing

The biggest billers aren't evenly distributed across the country. States with large Medicare populations and major medical centers dominate: California, Texas, Florida, and New York consistently produce the most high-billing providers. But per-capita billing concentration tells a different story — some smaller states with major health systems (like Minnesota with Mayo Clinic) show disproportionate billing per provider.

Scale vs. Scrutiny

The top 100 billers collectively process over 500 million services annually. At that volume, even automated quality checks miss patterns that would be obvious in smaller practices. When a lab processes 10,000 claims per day, a 0.1% error rate means 10 incorrect claims daily — over 2,500 per year.

Individual vs. Organizational NPIs

An important caveat when reading this list: some of these "providers" are organizations (Type 2 NPIs), while others are individual physicians (Type 1 NPIs). A single hospital system or national lab chain can bill under one organizational NPI, making their totals look enormous — because they represent thousands of individual clinicians working under one billing entity.

This distinction matters for fraud detection. An organization billing $500M is expected. An individual physician billing $50M deserves scrutiny. Our fraud analysis tools account for NPI type when flagging anomalies.

The question isn't whether big billers exist — it's whether the oversight matches the scale.

Related Investigations

💰 Medicare Millionaires🏢 The Rise of Corporate Medicine💲 The Medicare Markup Machine🧮 9,862 Services Per Day🧬 Genetic Testing Fraud👁️ Eye Care Billions🚨 Fraud Watchlist💊 The Drug Pipeline
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Continue Reading

Medicare Millionaires

The providers collecting $1M+ from Medicare annually.

The Markup Machine

Providers who charge Medicare far more than what's allowed.

9,862 Services Per Day

The impossible billing volumes hiding in Medicare data.

Eye Care Billions

How ophthalmology became Medicare's most expensive specialty.

Frequently Asked Questions

Who are the biggest Medicare billers in the United States?

The largest Medicare billers are predominantly clinical laboratory corporations. LabCorp, Quest Diagnostics, and other national lab chains consistently top the list, each collecting hundreds of millions in annual Medicare payments due to the sheer volume of diagnostic testing they process.

How much do the top 100 Medicare providers collect?

The top 100 Medicare providers collectively receive billions of dollars in payments annually. The concentration is remarkable — these 100 entities represent a tiny fraction of the 1.3 million Medicare providers but account for a disproportionate share of total spending.

Are the biggest Medicare billers committing fraud?

Not necessarily. Large billing volumes often reflect legitimate operations — national laboratory chains process millions of tests, and large health systems serve enormous patient populations. However, extreme billing concentration does warrant scrutiny, and some high-volume billers have been investigated for fraud.

Why do clinical laboratories bill so much to Medicare?

Clinical laboratories process massive volumes of diagnostic tests ordered by physicians across the country. A single patient visit may generate multiple lab tests, each billed separately. National chains like LabCorp and Quest serve millions of Medicare beneficiaries annually, creating enormous aggregate billing volumes.

How concentrated is Medicare spending among providers?

Medicare spending is highly concentrated. The top 1% of providers by billing volume account for approximately 25% of all Medicare Part B payments. The top 10% account for over 65%. This concentration reflects the dominance of large health systems, national labs, and high-volume specialty practices.

Data Sources

  • • CMS Medicare Provider Utilization and Payment Data (2014-2024)
  • • Physicians Advocacy Institute: Physician Practice Ownership Trends (2024)
  • • HHS OIG Reports on Laboratory Billing
  • • MedPAC Report to Congress, March 2026

Note: All data is from publicly available Medicare records. OpenMedicare is an independent journalism project not affiliated with CMS.